林育弘醫師 Yu-Hung Lin, MD PhD｜代謝減重外科・劍橋大學博士

🔪 手術專科領域 Surgical Specialties

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SASI / SASJ－雙通道

保留十二指腸通路，代謝改善佳 Dual-channel design preserving duodenal transit, with excellent metabolic outcomes

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袖狀胃切除術 Sleeve Gastrectomy

縮胃手術，相對單純，無腸道調整 Sleeve resection without intestinal rerouting — a simpler, well-established procedure

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OAGB－單接口胃繞道

單接口胃繞道，減重效果顯著，術後補充簡單 Single anastomosis gastric bypass with strong weight loss results and straightforward post-op supplementation

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機器手臂、腹腔鏡胃腸外科 Robotic & Laparoscopic GI Surgery

微創腹腔鏡及達文西機器手臂胃腸道手術及食道裂孔、抗胃酸逆流手術 Minimally invasive laparoscopic and robotic gastrointestinal surgery, including hiatal hernia repair and anti-reflux procedures

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機器手臂、腹腔鏡膽囊、疝氣手術 Robotic & Laparoscopic Cholecystectomy & Hernia Repair

單孔達文西膽囊摘除及腹股溝、腹壁疝氣手術 Single-port robotic cholecystectomy and inguinal/ventral hernia repair

🎓 學歷與培訓 Education & Training

2017 – 2022

臨床生化博士（PhD）｜英國劍橋大學 PhD in Clinical Biochemistry · University of Cambridge, UK

代謝科學研究所 Institute of Metabolic Science · 指導教授 Prof. Antonio Vidal-Puig · Dr Sergio Rodriguez-Cuenca Institute of Metabolic Science · Supervisors: Prof. Antonio Vidal-Puig · Dr Sergio Rodriguez-Cuenca

論文研究：THADA 基因在能量恆定中的角色 Thesis: The role of THADA in energy homeostasis

1999 – 2006

醫學士（MD）｜高雄醫學大學 Doctor of Medicine (MD) · Kaohsiung Medical University

醫學院醫學系 School of Medicine

🏥 現職與資歷 Positions & Career

2024 – 現在

國際醫療中心副主任 Deputy Director, International Medical Center

高雄長庚紀念醫院 Kaohsiung Chang Gung Memorial Hospital

2023 – 現在

一般外科副主任 Vice Chief, Division of General Surgery

高雄長庚紀念醫院 Kaohsiung Chang Gung Memorial Hospital

2017 – 現在

外科部助理教授 Assistant Professor of Surgery

長庚紀念醫院 Chang Gung Memorial Hospital

2012 – 2023

主治外科醫師・肝臟移植外科 Attending Surgeon, Liver Transplantation Programme

高雄長庚紀念醫院一般外科 Division of General Surgery, Kaohsiung Chang Gung Memorial Hospital

2007 – 2012

住院醫師・外科總醫師 Surgical Residency & Chief Resident

高雄長庚紀念醫院一般外科 Division of General Surgery, Kaohsiung Chang Gung Memorial Hospital

🔬 研究方向 Research Interests

林醫師的研究橫跨代謝外科手術成效、能量代謝生理學與分子機轉等領域。在英國劍橋大學攻讀博士期間，他專注於能量恆定相關基因 THADA 的功能，並深入探討肥胖與胰島素阻抗在脂肪組織中的調控機制。相關成果發表於 International Journal of Surgery、Nature Metabolism 等國際頂尖期刊，獲得學界高度肯定。 Dr Lin's research spans metabolic surgery outcomes, energy metabolism physiology, and molecular mechanisms of obesity. During his PhD at Cambridge, he investigated the function of the energy homeostasis gene THADA and explored the regulatory mechanisms of adipose tissue in obesity and insulin resistance. His findings have been published in top international journals including International Journal of Surgery and Nature Metabolism, receiving wide recognition in the academic community.

返台後，林醫師持續投入代謝手術長期成效的臨床研究，特別聚焦於 SASJ／SASI 術式的多中心資料分析，致力於建立更精準的代謝手術治療策略。 Back in Taiwan, Dr Lin continues clinical research into long-term metabolic surgery outcomes, with a particular focus on multi-centre data analysis of the SASJ/SASI procedure, working towards more precise treatment strategies in metabolic surgery.

在臨床方面，從一開始的肝臟手術、移植、胰臟手術到胃癌、膽囊、疝氣及減重手術，奠定了紮實的基礎。林醫師專精於微創腹部腸胃道手術，從早期腹腔鏡手術的發展，到現今的機器手臂輔助手術，皆持續精進技術並累積豐富經驗。 Clinically, Dr Lin built a solid foundation across liver surgery, transplantation, pancreatic surgery, gastric cancer, cholecystectomy, hernia repair, and bariatric surgery. He specialises in minimally invasive abdominal and gastrointestinal surgery, advancing his skills from early laparoscopic techniques through to today's robotic-assisted procedures.

代謝手術長期追蹤 Metabolic Surgery Outcomes SASI / SASJ 糖胖症治療 Diabesity Treatment 能量代謝基因體學 Energy Metabolism Genomics 脂肪組織發炎與纖維化 Adipose Tissue Fibro-inflammation GLP-1 / 腸泌素

📄 代表著作（精選） Selected Publications

Obes Surg 2025

單吻合袖狀腸道繞道術（SASJ）已成為台灣代謝減重手術首位 Single Anastomosis Sleeve Jejunal Bypass (SASJ) Has Become the Leading Metabolic Bariatric Surgery in Taiwan

Lin YH, Ser KH, Lee MH, Soong TC, Lee WJ · Obesity Surgery, 2025

Int J Surg 2026

SASJ 與袖狀胃切除術兩年成效比較：台灣多中心研究 Two-year outcomes of SASJ vs Sleeve Gastrectomy: A Taiwanese Multi-centre Study

Lin YH, Lee MH, Ser KH, Liu YY, Hsu CY, Soong TC, Lee WJ · International Journal of Surgery, 2026

Nature Metabolism 2022

肥胖中巨噬細胞 PEPD 失調決定脂肪組織發炎纖維化與胰島素阻抗 Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Pellegrinelli V, Rodriguez-Cuenca S, … Lin YH, … Vidal-Puig A · Nature Metabolism 4(4):476–494, 2022

Obes Surg 2016

垂直束帶胃縮術 15 年長期追蹤：與其他限制型術式之比較 15-year follow-up of vertical banded gastroplasty: comparison with other restrictive procedures

Lin YH, Lee WJ, Ser KH, Chen SC, Chen JC · Surgical Endoscopy 30(2):489–494, 2016

Obes Surg 2014

腹腔鏡袖狀胃切除術 vs 單接口胃繞道治療第二型糖尿病：五年隨機試驗結果 Laparoscopic Sleeve Gastrectomy Versus Single Anastomosis (Mini-) Gastric Bypass for T2DM: 5-Year Results of a Randomised Trial

Lee WJ, Chong K, Lin YH, Wei JH, Chen SC · Obesity Surgery 24(9):1552–1562, 2014

Obes Surg 2014

單接口胃繞道（SAGB/OAGB）：臨床證據評估 Single-Anastomosis Gastric Bypass (SAGB): Appraisal of Clinical Evidence

Lee WJ, Lin YH · Obesity Surgery 24(10):1749–1756, 2014

Ann Surg 2016

大型肝臟手術基準定義：5,202 名活體肝捐者多中心分析 Defining Benchmarks for Major Liver Surgery: A Multicentre Analysis of 5,202 Living Liver Donors

Rössler F, Sapisochin G, Song G, Lin YH, … Clavien PA · Annals of Surgery 264(3), 2016

* 完整著作列表請見 PubMed（共 37 篇 SCI 論文） * Full publication list available on PubMed (37 SCI-indexed papers)

🏅 專業資格與學會會籍 Credentials & Professional Memberships

台灣代謝及減重外科醫學會監事 Board Supervisor, Taiwan Society of Metabolic and Bariatric Surgery
台灣外科醫學會會員 Member, Taiwan Surgical Association
台灣胃腸外科醫學會會員 Member, Taiwan Surgical Society of Gastroenterology
台灣內視鏡外科醫學會會員 Member, Taiwan Association of Endoscopic Surgery
台灣肥胖醫學會會員 Member, Taiwan Medical Association for the Study of Obesity
台灣重症醫學會會員 Member, Taiwan Society of Critical Care Medicine
中華民國醫師執照 Medical License, Taiwan (ROC)

林育弘 醫師 Yu-Hung Lin, MD PhD